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Whose genome was first sequenced?

ScienceGeneticsTechnology

Quick Answer

The Human Genome Project (completed 2003) and Craig Venter's parallel effort decoded the human genome. It cost $2.7 billion and took 13 years. Today, sequencing a genome costs about $100 and takes hours.

The Full Story

The Human Genome Project (HGP), a publicly funded international effort launched in 1990, published its complete human genome sequence in April 2003 after 13 years and approximately $2.7 billion. Simultaneously, Craig Venter's private company Celera Genomics raced to complete its own version using "shotgun sequencing" and published a draft in 2001. The initial "reference" genome was actually a composite of several anonymous donors. The project revealed that humans have approximately 20,000–25,000 protein-coding genes (far fewer than the 100,000 originally expected). Today, thanks to next-generation sequencing technology, a full human genome can be sequenced in under 24 hours for approximately $100 β€” a price reduction of 99.9996%. This democratization has enabled personalized medicine, ancestry testing, and cancer genomics.

Key Facts

1.Completed: April 2003 after 13 years
2.Original cost: $2.7 billion
3.Current cost: ~$100

YouTube Angle

Suggested video title for this topic:

"From $2.7 Billion to $100 β€” The Incredible Shrinking Genome Cost"