👤 whose
Whose experiments helped reveal that DNA replication is semiconservative?
Human BiologyGenetics
Quick Answer
Matthew Meselson and Franklin Stahl showed in 1958 that DNA replicates semiconservatively. Their elegant density-labeling experiment became a classic in biology.
The Full Story
Matthew Meselson and Franklin Stahl used heavy nitrogen isotopes in E. coli to test how DNA copies itself. In 1958, they showed that after one round of replication, each DNA molecule contained one old strand and one new strand. This supported the semiconservative model proposed after the structure of DNA was solved. Their experiment is often called one of the most beautiful in biology.
Key Facts
1.Their experiment was published in 1958
2.They used nitrogen-15 and nitrogen-14
3.The result supported semiconservative replication
YouTube Angle
Suggested video title for this topic:
"The DNA experiment that proved how genes copy themselves"