Which vaccine was the first to eliminate a major childhood paralysis disease in many regions?

The polio vaccine, especially the inactivated polio vaccine developed by Jonas Salk and the oral polio vaccine developed by Albert Sabin, transformed global child health. Since mass vaccination began in the 1950s and 1960s, polio has been eliminated from most countries. Wild poliovirus remains endemic in only a small number of countries, making it one of the closest near-eradication campaigns in history. The fight continues because continued vaccination is needed until transmission is stopped everywhere.