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Which vaccine was the first to be made using recombinant DNA technology?

Quick Answer

The hepatitis B vaccine was the first major vaccine made with recombinant DNA technology. It was approved in the 1980s and produced without using human blood or plasma.

The Full Story

The hepatitis B vaccine became the first widely used vaccine produced through recombinant DNA technology, marking a major breakthrough in biotechnology. Instead of being made from blood-derived material, it uses a yeast system to produce hepatitis B surface antigen. This approach improved safety and manufacturing consistency. It also helped open the door to many later recombinant vaccines.

Key Facts

1.First recombinant vaccine: hepatitis B
2.Approved in the 1980s
3.Made using yeast-produced antigen

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"The first biotech vaccine changed how vaccines are made."

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