Which vaccine is the first to have been developed to prevent a cancer-causing infection that is transmitted mainly through skin contact?

HPV is transmitted primarily through intimate skin-to-skin contact, not by ordinary casual contact, and some types can cause cancer years later. The HPV vaccine was first licensed in 2006 and has become a routine adolescent vaccine in many countries. It is especially effective when given before exposure to the virus. By preventing infection with high-risk HPV types, it helps reduce the risk of cervical and other cancers later in life.