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Which human gene determines most cases of male biological sex development?

Quick Answer

The SRY gene is the main trigger for male sex development in typical human embryos. It is usually found on the Y chromosome.

The Full Story

SRY stands for sex-determining region Y. In typical development, this gene activates a chain of events that causes undifferentiated gonads to develop into testes. The testes then produce hormones that guide male sexual development. Although SRY is the key switch in most cases, sex development also depends on many other genes and hormones.

Key Facts

1.SRY is usually on the Y chromosome
2.It triggers testis development
3.Sex development involves many genes

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"One gene can start the cascade that shapes biological sex development."

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