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Which human gene is most commonly linked to hereditary breast and ovarian cancer?
Quick Answer
BRCA1 and BRCA2 are the key genes linked to hereditary breast and ovarian cancer. BRCA1 is often highlighted as one of the most important hereditary risk genes.
The Full Story
BRCA1 and BRCA2 help repair damaged DNA, especially double-strand breaks. Harmful mutations in either gene can greatly increase the risk of breast, ovarian, and some other cancers. BRCA1 was discovered in 1994, followed by BRCA2 in 1995. Genetic testing for these genes is now widely used to guide prevention and treatment decisions.
Key Facts
1.BRCA1 was identified in 1994
2.BRCA2 was identified in 1995
3.Mutations raise cancer risk
YouTube Angle
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"These two genes are famous because they help protect against cancer."
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