When was the first successful human larynx transplant performed?

The first successful larynx transplant, which restored a patient’s ability to speak and breathe with a transplanted voice box, was performed in 1998 in Cleveland. The operation was led by Dr. Marshall Strome. It was a major milestone because the larynx is essential for speech, swallowing, and airway protection. The case showed that very delicate composite transplants could be attempted in carefully selected patients.