When was the human heart first described in detail by a physician?

Galen of Pergamon, writing in the 2nd century CE, produced one of the most influential early anatomical descriptions of the heart. His ideas were based largely on animal dissection, but they dominated medical teaching in Europe and the Middle East for centuries. A more accurate understanding of the heart’s structure and function began to emerge much later, especially with William Harvey’s work in the 17th century. Harvey published his proof of blood circulation in 1628, which transformed cardiology and anatomy.