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Whose research first led to CRISPR gene editing?
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Quick Answer
Jennifer Doudna and Emmanuelle Charpentier turned CRISPR-Cas9 into a gene-editing tool. Their landmark paper was published in 2012.
The Full Story
Jennifer Doudna and Emmanuelle Charpentier are the scientists most closely associated with turning CRISPR-Cas9 into a programmable gene-editing technology. In 2012, they published a paper showing that the system could be directed to cut DNA at chosen locations. CRISPR had first been observed in bacteria as part of a natural immune defense, and their work transformed it into a powerful laboratory tool. They shared the 2020 Nobel Prize in Chemistry for this breakthrough.
Key Facts
1.Their key paper was published in 2012
2.They won the 2020 Nobel Prize in Chemistry
3.CRISPR was first discovered in bacteria
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Suggested video title for this topic:
"A bacterial defense system became one of the biggest tools in modern genetics."