Where was the first vaccine against human rotavirus largely tested in infants?

Rotavirus vaccine development involved multinational clinical trials rather than a single test site. Important studies were conducted in the United States, Finland, and several Latin American countries to ensure the vaccine worked across different populations. This was important because rotavirus burden is especially high in low- and middle-income countries. The evidence from these trials supported global rollout of newer vaccines after the first product was withdrawn. Today, rotavirus vaccination is part of infant schedules in many nations.