Where was the first smallpox vaccine developed?

Edward Jenner’s breakthrough took place in Berkeley, Gloucestershire, England, where he carried out his famous experiment in 1796. He used material from cowpox lesions to protect a boy from smallpox, helping launch modern immunization. Jenner’s work was published in 1798 and became the foundation of vaccination science. The word “vaccine” later came from the Latin word for cow, vacca, because of the cowpox connection. Smallpox was eventually eradicated worldwide in 1980.