Where was the first Ebola vaccine trial carried out?

The first major trial showing strong protection from an Ebola vaccine took place in Guinea in 2015 during a devastating West African outbreak. Researchers used a ring-vaccination strategy, vaccinating contacts of confirmed cases and their contacts. The vaccine candidate, rVSV-ZEBOV, later became the basis for licensed Ebola vaccines. The trial’s results were a turning point in outbreak control. Guinea’s participation was crucial to demonstrating that vaccination could help stop Ebola transmission in real time.