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What is telomerase?
Human BiologyEnzymes
Quick Answer
Telomerase is an enzyme that rebuilds telomeres, the protective ends of chromosomes. It is active in germ cells, stem cells, and many cancer cells.
The Full Story
Telomerase is a ribonucleoprotein enzyme that adds telomere repeats to chromosome ends. It uses an internal RNA template to extend DNA, helping counter the shortening that happens during cell division. In most adult body cells it is low or absent, which is one reason telomeres shorten over time. Its discovery and study have been central to understanding aging, stem cells, and cancer.
Key Facts
1.Telomerase extends chromosome ends using an internal RNA template
2.It is active in many germ cells and stem cells
3.Many cancers show increased telomerase activity
YouTube Angle
Suggested video title for this topic:
"The enzyme that helps cells keep their chromosome tips"