📖 what
What is cystic fibrosis?
Human BiologyGenetic Disorders
Quick Answer
Cystic fibrosis is an inherited disorder that affects the lungs and digestive system. It is caused by mutations in the CFTR gene.
The Full Story
Cystic fibrosis is a genetic disease caused by pathogenic variants in the CFTR gene, which helps control salt and water movement in cells. Thick, sticky mucus builds up in the lungs and other organs, leading to breathing problems, infections, and digestion issues. It is inherited in an autosomal recessive pattern, so a child must receive two altered copies of the gene to be affected. Treatments have improved greatly, including CFTR modulator drugs for many patients.
Key Facts
1.It is caused by mutations in the CFTR gene
2.It is inherited in an autosomal recessive pattern
3.Modern CFTR modulators help many patients
YouTube Angle
Suggested video title for this topic:
"The inherited disease that clogs lungs with thick mucus"