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What is a Barr body?

Human BiologyChromosomes

Quick Answer

A Barr body is an inactivated X chromosome visible as a dense spot in the nucleus. It is found in many cells of females and some other XX individuals.

The Full Story

A Barr body is the condensed, largely inactive form of one X chromosome in cells that undergo X-chromosome inactivation. It appears as a small dark-staining mass in the nucleus. The number of Barr bodies is usually one less than the number of X chromosomes present. It is a classic example of how chromosome biology can differ from the simple chromosome count taught in school.

Key Facts

1.Usually one Barr body forms for each X chromosome beyond the first
2.It is the inactive X chromosome
3.Named after geneticist Murray Barr

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Suggested video title for this topic:

"The hidden chromosome lump inside the nucleus"