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What are induced pluripotent stem cells?
GeneticsStem Cells
Quick Answer
Induced pluripotent stem cells, or iPSCs, are adult cells reprogrammed back into a stem-cell-like state. They can then be turned into many other cell types.
The Full Story
Induced pluripotent stem cells are made by inserting a small set of genes or factors that reset adult cells to a pluripotent state. This breakthrough was first reported in 2006 in mice and in 2007 in human cells by Shinya Yamanakaβs work. iPSCs can be used to study diseases, test drugs, and potentially create patient-specific tissues. They transformed modern regenerative biology and earned Yamanaka the 2012 Nobel Prize.
Key Facts
1.First mouse iPSCs were reported in 2006
2.Human iPSCs were reported in 2007
3.Shinya Yamanaka received the 2012 Nobel Prize
YouTube Angle
Suggested video title for this topic:
"How ordinary cells are reprogrammed into stem cells"