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How Do Vaccines Create Immunity?

MedicineBiology

Quick Answer

Vaccines train the immune system by exposing it to a harmless version of a pathogen, prompting it to produce antibodies and memory cells.

The Full Story

Vaccines work by mimicking an infection without causing disease. They introduce an antigen — a weakened or inactivated pathogen, a piece of it (like a protein), or its genetic instructions (mRNA) — into the body. The immune system recognises the antigen as foreign and mounts a response: B cells produce antibodies that neutralise the antigen, while T cells destroy infected cells. Crucially, some of these cells become long-lived memory cells. If the real pathogen later enters the body, the immune system recognises it immediately and mounts a rapid, strong response, preventing illness or reducing its severity. This process is the basis of immunological memory.

Key Facts

1.mRNA vaccines (like those for COVID-19) instruct cells to produce a harmless spike protein, triggering an immune response without using any virus.
2.Herd immunity is achieved when enough of a population is immunised (typically 80-95% depending on the disease) to protect unvaccinated individuals.
3.Vaccines have eradicated smallpox and nearly eliminated polio, measles, and diphtheria from much of the world.

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Suggested video title for this topic:

"How Vaccines Train Your Immune System — From Injection to Immunity"