How do tuberculosis vaccines differ from most other vaccines?
Quick Answer
The classic BCG vaccine is made from a weakened bacterium related to TB, not from a killed germ or mRNA. It is especially useful in protecting young children against severe forms of tuberculosis.
The Full Story
The Bacille Calmette-Guérin, or BCG, vaccine was developed in the early 20th century by Albert Calmette and Camille Guérin. It is derived from a weakened strain of Mycobacterium bovis and has been used for over a century. BCG does not prevent all pulmonary tuberculosis in adults, but it can strongly protect infants and children against severe TB forms such as meningitis. For that reason it remains part of routine immunization in many countries with high TB burden.
Key Facts
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"How a century-old vaccine still helps fight tuberculosis"